Synthetic subaperture-based angle-independent Doppler flow measurements using single-beam line field optical coherence tomography in vivo

Opt Lett. 2019 Feb 15;44(4):967-970. doi: 10.1364/OL.44.000967.

Abstract

We demonstrate a synthetic subaperture-based angle-independent Doppler flow calculation, using a line field spectral domain optical coherence tomography system. The high speed of the system features a high phase stability over the volume, which is necessary to apply synthetic subapertures in the aperture plane. Thus, the flow component for each subaperture can be reconstructed in postprocessing. Capillary phantom and in vivo retinal imaging experiments were performed to validate and demonstrate angle-independent Doppler flow calculation.

MeSH terms

  • Humans
  • Imaging, Three-Dimensional
  • Phantoms, Imaging
  • Regional Blood Flow*
  • Retinal Vessels / diagnostic imaging*
  • Retinal Vessels / physiology*
  • Tomography, Optical Coherence*