Proteome profiling of secreted and membrane vesicle associated proteins of an invasive and a commensal Staphylococcus haemolyticus isolate

Jorunn Pauline Cavanagh; Fatemeh Askarian; Maria Pain; Jack-Ansgar Bruun; Ilona Urbarova; Sun Nyunt Wai; Frank Schmidt; Mona Johannessen

doi:10.1016/j.dib.2018.11.147

Proteome profiling of secreted and membrane vesicle associated proteins of an invasive and a commensal Staphylococcus haemolyticus isolate

Data Brief. 2019 Jan 11:22:914-919. doi: 10.1016/j.dib.2018.11.147. eCollection 2019 Feb.

Authors

Jorunn Pauline Cavanagh^{1

2}, Fatemeh Askarian^{3

4}, Maria Pain², Jack-Ansgar Bruun⁵, Ilona Urbarova⁵, Sun Nyunt Wai⁶, Frank Schmidt^{7

8}, Mona Johannessen³

Affiliations

¹ Department of Paediatrics, University Hospital of North Norway, Tromsø, Norway.
² Paediatric Research Group, Department of Clinical Medicine, Faculty of Health Sciences, UiT - The Arctic University of Norway, Tromsø, Norway.
³ Research Group of Host Microbe interaction, Department of Medical Biology, UiT- The Arctic University of Norway, Tromsø, Norway.
⁴ Faculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences (NMBU), 1432 Ås, Norway.
⁵ Proteomics Platform Facility, Department of Medical Biology, UiT - The Arctic University of Norway, Tromsø, Norway.
⁶ Department of Molecular Biology, Umeå University, Sweden.
⁷ Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.
⁸ Proteomics Core, Weill Cornell Medicine-Qatar, Education City, PO 24144, Doha, Qatar.

Abstract

Bacterial membrane vesicles (MVs) mediate bacterial virulence by enabling secretion and long distance delivery of bacterial effector molecules. Staphylococcus haemolyticus has now been demonstrated to produce membrane vesicles (MVs). The protein content of S. haemolyticus MVs was identified by Mass spectrometry and compared to proteins identified in the total secretome. This information is presented in this data article. Further background and interpretation of the data can be found in the article: Comparative exoproteome profiling of an invasive and a commensal S. haemolyticus isolate (Cavanagh et al., in press). Data are available via Proteome Xchange with identifier PXD010389.