Long-Term Survival After Brain and Spine Metastasis in Malignant Melanoma

World Neurosurg. 2019 May:125:164-169. doi: 10.1016/j.wneu.2019.01.215. Epub 2019 Feb 11.

Abstract

Background: Metastasis from melanoma carries poor prognosis and survival. Average life expectancy is estimated 4 to 6 months after diagnosis of skeletal metastasis. Comprehensive treatment, along with newer immunotherapies, has shown promising results.

Case description: We report a case of long-term survival after metastasis to the brain and spine and discuss associated factors.

Conclusions: Our report emphasizes the importance of regular and critical surveillance of the disease and aggressive surgical and medical management in melanoma.

Keywords: Cancer; Melanoma; Metastasis; Survival.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain Neoplasms / mortality
  • Brain Neoplasms / secondary*
  • Brain Neoplasms / therapy
  • Combined Modality Therapy / methods
  • Humans
  • Male
  • Melanoma / mortality*
  • Melanoma / pathology*
  • Melanoma / therapy*
  • Melanoma, Cutaneous Malignant
  • Skin Neoplasms / mortality*
  • Skin Neoplasms / pathology*
  • Skin Neoplasms / therapy*
  • Spinal Neoplasms / mortality
  • Spinal Neoplasms / secondary*
  • Spinal Neoplasms / therapy