Dynamic Load Balancing Strategy for Parallel Tumor Growth Simulations

J Integr Bioinform. 2019 Feb 14;16(1):20180066. doi: 10.1515/jib-2018-0066.

Abstract

In this paper, we propose a parallel cellular automaton tumor growth model that includes load balancing of cells distribution among computational threads with the introduction of adjusting parameters. The obtained results show a fair reduction in execution time and improved speedup compared with the sequential tumor growth simulation program currently referenced in tumoral biology. The dynamic data structures of the model can be extended to address additional tumor growth characteristics such as angiogenesis and nutrient intake dependencies.

Keywords: Cellular Automaton; High Performance Computing; Mathematical Oncology; Parallel Programming; Tumoral Growth Simulation.

MeSH terms

  • Algorithms*
  • Cell Proliferation*
  • Computational Biology / methods*
  • Computer Simulation*
  • Humans
  • Models, Biological*
  • Neoplasms / pathology*
  • Tumor Cells, Cultured