Synthesis of 4-Alkyl-4 H-1,2,4-triazole Derivatives by Suzuki Cross-coupling Reactions and Their Luminescence Properties

Molecules. 2019 Feb 12;24(3):652. doi: 10.3390/molecules24030652.

Abstract

New derivatives of 4-alkyl-3,5-diaryl-4H-1,2,4-triazole were synthesized utilizing the Suzuki cross-coupling reaction. The presented methodology comprises of the preparation of bromine-containing 4-alkyl-4H-1,2,4-triazoles and their coupling with different commercially available boronic acids in the presence of ionic liquids or in conventional solvents. The obtained compounds were tested for their luminescence properties.

Keywords: 1,2,4-triazole derivatives; Suzuki cross-coupling; heterocycles; ionic liquids; luminescence properties.

MeSH terms

  • Boronic Acids / chemistry
  • Bromine / chemistry
  • Luminescence
  • Solvents / chemistry
  • Triazoles / chemistry*

Substances

  • Boronic Acids
  • Solvents
  • Triazoles
  • 1,2,4-triazole
  • Bromine