Neuroimaging in Functional Movement Disorders

Curr Neurol Neurosci Rep. 2019 Feb 12;19(3):12. doi: 10.1007/s11910-019-0926-y.

Abstract

Purpose of review: Functional movement disorders are common and disabling causes of abnormal movement control. Here, we review the current state of the evidence on the use of neuroimaging in Functional movement disorders, particularly its role in helping to unravel the pathophysiology of this enigmatic condition.

Recent findings: In recent years, there has been a shift in thinking about functional movement disorder, away from a focus on high-level psychological precipitants as in Freudian conversion theories, or even an implicit belief they are 'put-on' for secondary gain. New research has emphasised novel neurobiological models incorporating emotional processing, self-representation and agency. Neuroimaging has provided new insights into functional movement disorders, supporting emerging neurobiological theories implicating dysfunctional emotional processing, self-image and sense of agency. Recent studies have also found subtle structural brain changes in patients with functional disorders, arguing against a strict functional/structural dichotomy.

Keywords: Conversion disorder; Functional movement disorders; Imaging; MRI; Psychogenic; fMRI.

Publication types

  • Review

MeSH terms

  • Brain / diagnostic imaging*
  • Brain / physiopathology
  • Dyskinesias / diagnostic imaging
  • Dyskinesias / physiopathology
  • Humans
  • Movement Disorders / diagnostic imaging*
  • Movement Disorders / physiopathology
  • Neuroimaging / methods*