Background: Nevus Sebaceous (NS) is hamartoma predominantly composed of sebaceous glands and is classified as a type of epidermal nevus. In most case, clinical manifestation of NS is typical, so histopathology examination is important only in atypical lesions for its risk of malignancy. Clinical symptoms are plaques or papules (100%), appearing in the head area (100%) with smooth surface (65.8%), usually with hair loss (60.7%). The histopathology is mostly characterized by the image of sebaceous gland hyperplasia (100%), no hair follicles (60.7%) or immature follicles (14.3%).
Aim: The aim of our study is describing clinical and histopathological manifestation, make diagnosis and evaluate the best therapy.
Methods: Our study recruited 38 patients with NS, 3 patients (7.9%) with atypical aspects. All patients were treated by surgical excision.
Results: Complications as hair loss and infections were reported in 36.8% patients. No patients had recurrence after one year of treatment.
Conclusion: Based upon our experience, surgery is cheap, simple, associated with high aesthetics effectiveness and low recurrence rate, proposing as the first choice for treatment of NS.
Keywords: Epidermal nevus; Nevus; Nevus sebaceous; Sebaceous.