The impact of sedentary behavior patterns on carotid atherosclerotic burden: Implications from the Corinthia epidemiological study

Atherosclerosis. 2019 Mar:282:154-161. doi: 10.1016/j.atherosclerosis.2019.01.026. Epub 2019 Jan 29.

Abstract

Background and aims: Sedentary lifestyle, unlike leisure time physical activity (PA), is associated with atherosclerosis progression. Regarding the interrelationship between television watching, as a sedentary behavior pattern, and cardiovascular disease burden, few data exist.

Methods: In this cross-sectional epidemiological study based on 2043 inhabitants of the Corinthia region, in Greece, ultrasonography was used to measure carotid intima-media thickness (IMT) in both carotid arteries. The average (meanIMT) and maximum thickness (maxIMT) were determined as representative values of subclinical atherosclerosis. We evaluated PA using the self-reported International Physical Activity Questionnaire (IPAQ). Based on specific questions, the average hours per week spent on watching television (TV), videos or DVD was calculated for each participant.

Results: According to TV viewing time, subjects were categorized into the low (≤7 h/week), moderate (7˃ TV hours/week ≤21) and high (˃21 h/week) TV viewing time groups. Prevalence of carotid atheromatic plaque was lower in the low TV viewing time group compared to the moderate and high TV viewing time groups (p = 0.02). TV viewing time was associated with increased carotid IMT (p = 0.03) and the prevalence of carotid atheromatic plaque (p = 0.02), even after adjustment for age, body mass index, cardiovascular risk factors or history of cardiovascular disease. Subjects in the high TV viewing time group have 80% increase odds of carotid atheromatic plaque compared to patients categorized in the low TV viewing time group (p = 0.01).

Conclusions: The present findings have important public health implications, providing a better understanding of the components of sedentary behavior that are associated with atherosclerotic progression.

Keywords: Atherosclerosis; Carotid intima-media thickness; Corinthia study; Physical activity; Sedentary behavior; Television viewing.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Carotid Artery Diseases / epidemiology*
  • Carotid Artery Diseases / physiopathology
  • Carotid Intima-Media Thickness
  • Cross-Sectional Studies
  • Disease Progression
  • Exercise
  • Female
  • Greece / epidemiology
  • Humans
  • Hypertension / epidemiology*
  • Hypertension / physiopathology
  • Inflammation
  • Male
  • Middle Aged
  • Sedentary Behavior*
  • Self Report
  • Surveys and Questionnaires
  • Television*