Structural modification of trilobolide for upgrading its immunobiological properties and reducing its cytotoxic action

Fitoterapia. 2019 Apr:134:88-95. doi: 10.1016/j.fitote.2019.02.002. Epub 2019 Feb 4.

¹ Institute of Organic Chemistry and Biochemistry, The Czech Academy of Sciences, CZ-166 10 Prague 6, Czech Republic. Electronic address: harmatha@uochb.cas.cz.
² Institute of Organic Chemistry and Biochemistry, The Czech Academy of Sciences, CZ-166 10 Prague 6, Czech Republic.
³ University of Chemistry and Technology in Prague, CZ-1660 10 Prague 6, Czech Republic.
⁴ Institute of Experimental Medicine, The Czech Academy of Sciences, CZ-142 20 Prague 4, Czech Republic.
⁵ Institute of Experimental Medicine, The Czech Academy of Sciences, CZ-142 20 Prague 4, Czech Republic; Department of Pharmacology and Toxicology, Faculty of Medicine in Pilsen, Charles University, 323 00 Pilsen, Czech Republic.
⁶ Department of Pharmacology and Toxicology, Faculty of Medicine in Pilsen, Charles University, 323 00 Pilsen, Czech Republic; Biomedical Centre, Faculty of Medicine in Pilsen, Charles University, CZ-323 00 Pilsen, Czech Republic.

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