Analysis of Bone Architecture in Rodents Using Micro-Computed Tomography

Methods Mol Biol. 2019:1914:507-531. doi: 10.1007/978-1-4939-8997-3_28.

Abstract

This chapter describes the use of micro-computed tomography scanning for analyzing bone structure, focussing on rodent bone. It discusses sample preparation, the correct setup of the scanner, the impact of some of the important scanner settings and new applications.

Keywords: 3D; Computerized tomography; Imaging CT; Micro-CT; Rodent; X-ray.

MeSH terms

  • Animals
  • Biopsy
  • Bone Density
  • Bone and Bones / anatomy & histology
  • Bone and Bones / diagnostic imaging*
  • Bone and Bones / pathology
  • Female
  • Histocytological Preparation Techniques / instrumentation
  • Histocytological Preparation Techniques / methods
  • Humans
  • Imaging, Three-Dimensional / instrumentation
  • Imaging, Three-Dimensional / methods*
  • Mice
  • Models, Animal
  • Rats
  • Software
  • X-Ray Microtomography / instrumentation
  • X-Ray Microtomography / methods*