Histomorphometry in Rodents

Reinhold G Erben; Martin Glösmann

doi:10.1007/978-1-4939-8997-3_24

Histomorphometry in Rodents

Methods Mol Biol. 2019:1914:411-435. doi: 10.1007/978-1-4939-8997-3_24.

Authors

Reinhold G Erben¹, Martin Glösmann²

Affiliations

¹ Department of Biomedical Sciences, Institute of Physiology, Pathophysiology, and Biophysics, University of Veterinary Medicine, Vienna, Austria. Reinhold.Erben@vetmeduni.ac.at.
² VetCore Facility for Research, University of Veterinary Medicine, Vienna, Austria.

PMID: 30729480
DOI: 10.1007/978-1-4939-8997-3_24

Abstract

Bone histomorphometry remains an important tool with which to study the pathophysiology of bone disease and the cellular mechanism by which treatments work. Here we review the methods for embedding, sectioning, staining, and analysis of bone sections in rodents.

Keywords: Bone; Bone remodeling; Histomorphometry; Osteoblast; Osteoclast.

Publication types

Review

MeSH terms

Animals
Bone Diseases / pathology*
Bone Remodeling / physiology
Bone and Bones / pathology*
Histocytological Preparation Techniques / instrumentation
Histocytological Preparation Techniques / methods*
Image Processing, Computer-Assisted / instrumentation
Image Processing, Computer-Assisted / methods
Mice
Microscopy / instrumentation
Microscopy / methods
Rats
Software