The effects of heated humidification to nasopharynx on nasal resistance and breathing pattern

PLoS One. 2019 Feb 6;14(2):e0210957. doi: 10.1371/journal.pone.0210957. eCollection 2019.

Abstract

Background: Mouth breathing could induce not only dry throat and eventually upper respiratory tract infection, but also snoring and obstructive sleep apnea, while nasal breathing is protective against those problems. Thus, one may want to explore an approach to modify habitual mouth breathing as preferable to nasal breathing. The aim of this study was to investigate the physiological effects of our newly developed mask on facilitation of nasal breathing.

Methods: Thirty seven healthy male volunteers were enrolled in a double blind, randomized, placebo-controlled crossover trial. Participants wore a newly developed heated humidification mask or non-heated-humidification mask (placebo) for 10-min each. Subjective feelings including dry nose, dry throat, nasal obstruction, ease to breathe, relaxation, calmness, and good feeling were asked before and after wearing each mask. In addition, the effects of masks on nasal resistance, breathing pattern, and heart rate variability were assessed.

Results: Compared with the placebo mask, the heated humidification mask improved all components of subjective feelings except for ease to breathe; moreover, decreased nasal resistance and respiratory frequency accompanied a simultaneous increase in a surrogate maker for tidal volume. However, use of the heated humidification mask did not affect heart rate variability.

Conclusion: Adding heated humidification to the nasopharynx could modulate breathing patterns with improvement of subjective experience and objective nasal resistance.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Cross-Over Studies
  • Double-Blind Method
  • Healthy Volunteers
  • Hot Temperature / therapeutic use*
  • Humans
  • Humidity*
  • Male
  • Masks
  • Middle Aged
  • Mouth Breathing / therapy*
  • Nasopharynx / physiology*
  • Respiration*

Grants and funding

This study was funded by Kao Corporation. However, the funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. H Oda and M Igaki are employees of the Kao Corporation. However, as we described at the section of Author Contribution in the main text, H Oda and M Igaki contributed only to the data collection. They have not been involved in other roles at all.