Case Report and Literature Review of Nodular Hiradenoma, a Rare Adnexal Tumor That Mimics Breast Carcinoma, in a 20-Year-Old Woman

Lab Med. 2019 Jul 16;50(3):320-325. doi: 10.1093/labmed/lmy084.

Abstract

Nodular hidradenoma is an uncommon cutaneous adnexal tumor arising from sweat glands. In the skin, it usually presents as a solitary dermal nodule; excision is curative in most cases. In rare instances, it may present as a breast mass and can mimic breast carcinoma clinically and radiologically, causing diagnostic dilemmas for the treating physician and pathologist. Herein, we discuss a case of nodular hidradenoma in a 20-year-old Hispanic woman as a rapidly growing mass in the breast that mimicked breast carcinoma. We discuss the rare presentation of this uncommon tumor and the differential diagnosis of this entity, as well as the results of our literature review on the topic.

Keywords: adnexal tumor; breast; breast carcinoma; clear cell hidradenoma; hidradenoma; nodular hidradenoma.

Publication types

  • Case Reports

MeSH terms

  • Acrospiroma / diagnosis*
  • Acrospiroma / pathology*
  • Breast / pathology
  • Breast Neoplasms / pathology*
  • Diagnosis, Differential
  • Female
  • Histocytochemistry
  • Humans
  • Immunohistochemistry
  • Sweat Gland Neoplasms / diagnosis*
  • Sweat Gland Neoplasms / pathology*
  • Young Adult