Bullous lupus erythematosus with an erythema gyratum repens-like pattern

Dermatol Online J. 2019 Jan 15;25(1):13030/qt0nt6h49v.

Abstract

Bullous lupus erythematosus is a rare clinical form of lupus. The diagnosis is challenging and involves the exclusion of other subepidermal bullous dermatoses. We present a 21-year-old woman with erythematosus, polycyclic plaques with vesiculobullae along the periphery, creating an erythema gyratum repens-like pattern on acral regions. The cutaneous biopsy, analytical, and autoimmune studies support the diagnosis of systemic lupus erythematosus. Dapsone and glucocorticosteroids were given with prompt resolution of the lesions within two weeks. To our knowledge this is the first case of bullous lupus erythematosus with this atypical acral presentation.

Publication types

  • Case Reports

MeSH terms

  • Anti-Infective Agents / therapeutic use
  • Dapsone / therapeutic use
  • Erythema
  • Female
  • Foot Dermatoses / diagnosis*
  • Foot Dermatoses / drug therapy
  • Foot Dermatoses / etiology
  • Foot Dermatoses / pathology
  • Glucocorticoids / therapeutic use
  • Hand Dermatoses / diagnosis*
  • Hand Dermatoses / drug therapy
  • Hand Dermatoses / etiology
  • Hand Dermatoses / pathology
  • Humans
  • Leg Dermatoses / diagnosis*
  • Leg Dermatoses / drug therapy
  • Leg Dermatoses / etiology
  • Leg Dermatoses / pathology
  • Lupus Erythematosus, Systemic / complications
  • Lupus Erythematosus, Systemic / diagnosis*
  • Lupus Erythematosus, Systemic / immunology
  • Lupus Erythematosus, Systemic / pathology
  • Skin Diseases, Vesiculobullous / diagnosis*
  • Skin Diseases, Vesiculobullous / drug therapy
  • Skin Diseases, Vesiculobullous / etiology
  • Skin Diseases, Vesiculobullous / pathology
  • Young Adult

Substances

  • Anti-Infective Agents
  • Glucocorticoids
  • Dapsone