Clinical outcomes of hemodialysis patients in a public-private partnership care framework in Italy: a retrospective cohort study

BMC Nephrol. 2019 Feb 1;20(1):35. doi: 10.1186/s12882-019-1224-2.

Abstract

Background: Innovative care models such as public-private partnerships (PPPs) may help meet the challenge of providing cost-effective high-quality care for the steadily growing and complex chronic kidney disease population since they combine the expertise and efficiency of a specialized dialysis provider with the population care approach of a public entity. We report the five-years main clinical outcomes of a population of patients treated on hemodialysis within a PPP-care model in Italy.

Methods: This descriptive retrospective cohort study consisted of all consecutive hemodialysis patients treated in the NephroCare-operated Nephrology and Dialysis unit of the Seriate Hospital in 2012-2016, which exercises a PPP-care model. Clinical and treatment information was obtained from the European Clinical Database. Hospitalization outcomes and cumulative all-cause mortality incidences that accounted for competing risks were calculated.

Results: We included 401 hemodialysis patients (197 prevalent and 204 incident patients) in our study. The mean cohort age and age-adjusted Charlson Comorbidity Index were 67.0 years and 6.7, respectively. Patients were treated with online high-volume hemodiafiltration or high-flux hemodialysis. Parameters of treatment efficiency were above the recommended targets throughout the study period. Patients in the PPP experienced benefits in terms of hospitalization (average number of hospital admissions/patient-year: 0.79 and 1.13 for prevalent and incident patients, respectively; average length of hospitalization: 8.9 days for both groups) and had low cumulative all-cause mortality rates (12 months: 10.6 and 7.8%, 5 years: 42.0 and 35.9%, for prevalent and incident patients, respectively).

Conclusions: Results of our descriptive study suggest that hemodialysis patients treated within a PPP-care model framework received care complying with recommended treatment targets and may benefit in terms of hospitalization and mortality outcomes.

Keywords: Hemodialysis, Hemodiafiltration, Survival, Outcome, Hospitalization, Outsourcing, Public private partnership.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Comorbidity
  • Female
  • Follow-Up Studies
  • Hemodiafiltration / statistics & numerical data
  • Hemodialysis Units, Hospital
  • Hospitalization / statistics & numerical data
  • Humans
  • Incidence
  • Italy / epidemiology
  • Kidney Failure, Chronic / epidemiology
  • Kidney Failure, Chronic / therapy
  • Male
  • Middle Aged
  • Mortality
  • Prevalence
  • Public-Private Sector Partnerships*
  • Renal Dialysis / statistics & numerical data*
  • Retrospective Studies
  • Treatment Outcome
  • Vascular Access Devices