Metabolomics Analysis of Glutamate Receptor Function

Methods Mol Biol. 2019:1941:155-165. doi: 10.1007/978-1-4939-9077-1_11.

Abstract

Metabolomics analysis provides a unique opportunity for comprehensive mapping of glutamatergic system function using high-throughput metabolite analysis and providing a perspective of the enzymatic activity, which cannot be obtained by other systems biology techniques.

Keywords: Brain; Gas chromatography; Glutamate; Glutamate receptor; Mass spectrometry; Metabolites; Metabolomics.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Gas Chromatography-Mass Spectrometry / methods*
  • Glutamic Acid / metabolism*
  • Humans
  • Metabolomics*
  • Receptors, Glutamate / physiology*

Substances

  • Receptors, Glutamate
  • Glutamic Acid