Synovial sarcoma in an HIV-positive pregnant woman and review of literature

BMJ Case Rep. 2019 Jan 29;12(1):e227646. doi: 10.1136/bcr-2018-227646.

Abstract

We present a first case of synovial sarcoma in an HIV-positive pregnant woman. This 28-year-old woman was diagnosed with synovial sarcoma, a high-grade malignant soft tissue sarcoma, involving her left thigh during the first trimester of her pregnancy. She underwent surgical treatment in the form of hip disarticulation at 30 weeks' gestation. She was subsequently delivered by emergency caesarean section (CS) at 34 weeks' gestation when she presented with wound sepsis and a scan revealed static growth in a small for gestational age fetus. Prompt diagnosis and treatment of this aggressive tumour is important and should involve a multidisciplinary approach, with a balanced consideration of the maternal and fetal outcomes.

Keywords: HIV / aids; oncology; orthopaedics; pregnancy.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Cesarean Section
  • Diagnosis, Differential
  • Female
  • HIV Infections / complications*
  • Humans
  • Infant, Newborn
  • Magnetic Resonance Imaging
  • Pregnancy
  • Pregnancy Complications, Neoplastic / diagnosis*
  • Pregnancy Complications, Neoplastic / surgery
  • Sarcoma, Synovial / complications*
  • Sarcoma, Synovial / diagnosis*
  • Sarcoma, Synovial / surgery
  • Thigh / diagnostic imaging
  • Thigh / surgery