Sex-based differences of the tumor mutational burden and T-cell inflammation of the tumor microenvironment

Ann Oncol. 2019 Apr 1;30(4):653-655. doi: 10.1093/annonc/mdz034.
No abstract available

Publication types

  • Letter

MeSH terms

  • Antibodies, Monoclonal, Humanized / pharmacology*
  • Antibodies, Monoclonal, Humanized / therapeutic use
  • Antineoplastic Agents, Immunological / pharmacology*
  • Antineoplastic Agents, Immunological / therapeutic use
  • Biomarkers, Tumor / genetics
  • Drug Resistance, Neoplasm / genetics
  • Drug Resistance, Neoplasm / immunology
  • Female
  • Health Status Disparities*
  • Humans
  • Inflammation / immunology*
  • Male
  • Mutation Rate
  • Neoplasms / drug therapy*
  • Neoplasms / genetics
  • Neoplasms / immunology
  • Predictive Value of Tests
  • Prognosis
  • Sex Factors
  • T-Lymphocytes / immunology
  • Treatment Outcome
  • Tumor Microenvironment / immunology

Substances

  • Antibodies, Monoclonal, Humanized
  • Antineoplastic Agents, Immunological
  • Biomarkers, Tumor
  • pembrolizumab