Metastatic calcinosis cutis in a patient with Hodgkin's lymphoma

Dermatol Online J. 2018 Nov 15;24(11):13030/qt7z73b3kk.

Abstract

Calcinosis cutis results from the deposition of insoluble calcium salts in the skin and subcutaneous tissue. Herein, we report a case of extensive metastatic calcinosis cutis in an 18-year-old woman with stage IV Hodgkin lymphoma with skeletal involvement. With combination therapy including radiation directed at her lymphoma and diltiazem, her lesions improved dramatically. This case demonstrates the previously unreported association between calcinosis cutis and Hodgkin lymphoma.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Bone Neoplasms / secondary
  • Calcinosis / diagnosis*
  • Calcinosis / etiology
  • Calcinosis / pathology
  • Calcium Channel Blockers / therapeutic use
  • Diltiazem / therapeutic use
  • Female
  • Hodgkin Disease / complications
  • Hodgkin Disease / drug therapy
  • Hodgkin Disease / pathology
  • Hodgkin Disease / radiotherapy*
  • Humans
  • Hypercalcemia / diagnosis*
  • Hypercalcemia / drug therapy
  • Hypercalcemia / etiology
  • Neoplasm Staging
  • Skin Diseases, Metabolic / diagnosis*
  • Skin Diseases, Metabolic / etiology
  • Skin Diseases, Metabolic / pathology

Substances

  • Calcium Channel Blockers
  • Diltiazem