RETRACTED: Silence of lncRNA CHRF protects H9c2 cells against lipopolysaccharide-induced injury via up-regulating microRNA-221

Exp Mol Pathol. 2019 Apr:107:43-50. doi: 10.1016/j.yexmp.2019.01.010. Epub 2019 Jan 26.

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief. Given the comments of Dr Elisabeth Bik regarding this article “… the Western blot bands in all 400+ papers are all very regularly spaced and have a smooth appearance in the shape of a dumbbell or tadpole, without any of the usual smudges or stains. All bands are placed on similar looking backgrounds, suggesting they were copy/pasted from other sources, or computer generated”, the journal requested the authors to provide the raw data. However, the authors were not able to fulfil this request and therefore the Editor-in-Chief decided to retract the article.

Keywords: H9c2 cell; Lipopolysaccharide (LPS); LncRNA CHRF; Myocarditis; miR-221.

Publication types

  • Retracted Publication

MeSH terms

  • Animals
  • Cell Line
  • Gene Knockdown Techniques
  • Lipopolysaccharides / toxicity
  • MicroRNAs / metabolism*
  • Myoblasts
  • Myocarditis / metabolism*
  • Myocytes, Cardiac / metabolism*
  • Myocytes, Cardiac / pathology
  • RNA, Long Noncoding / genetics*
  • Rats
  • Up-Regulation

Substances

  • Lipopolysaccharides
  • MIRN221 microRNA, rat
  • MicroRNAs
  • RNA, Long Noncoding