Elevated umbilical cord arterial lactate at birth and electronic fetal monitoring characteristics on admission and in the active phase

J Perinatol. 2019 Mar;39(3):481-487. doi: 10.1038/s41372-019-0324-y. Epub 2019 Jan 28.

Abstract

Objective: To investigate the association between elevated umbilical arterial lactate at birth and electronic fetal monitoring (EFM) characteristics at admission and in the beginning of the active phase of labor.

Study design: Nested case-control study within a prospective cohort of laboring patients at term who achieved active labor. Neonates with umbilical arterial lactate ≥ 4 mmol/L (cases, n = 119), were matched 1:1 to controls with lactate < 4 mmol/L. EFM patterns were compared with multivariable logistic regression.

Result: There were no differences in EFM parameters in the first 60 minutes after admission. At the beginning of active labor, 13.5% of cases and 26.1% of controls had always category I tracings, adjusted odds ratio 0.48, 95% confidence interval 0.24-0.94). Cases were less likely to have an always category I tracing from admission into the active phase.

Conclusion: Elevated umbilical arterial lactate at birth is associated with distinct EFM patterns early in the labor course.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Adult
  • Apgar Score
  • Cardiotocography / instrumentation*
  • Case-Control Studies
  • Female
  • Fetal Blood / chemistry*
  • Heart Rate, Fetal*
  • Humans
  • Labor, Obstetric*
  • Lactates / blood*
  • Logistic Models
  • Male
  • Multivariate Analysis
  • Pregnancy
  • Prospective Studies
  • Young Adult

Substances

  • Lactates