[A Case of Choriocarcinoma of the Small Intestine with Multiple Lung and Liver Metastases]

Gan To Kagaku Ryoho. 2018 Dec;45(13):2102-2104.
[Article in Japanese]

Abstract

A 73-year-old male presented with melena and severe anemia. An esophagogastroduodenoscopy(EGD)and colonoscopy( CS)revealed no source of hemorrhage. Multiple small intestinal tumors were observed on abdominal ultrasound(US). CT also showed mesenteric lymph node metastases and multiple lung and liver metastases. Since active bleeding was suspected, we performed an emergency surgery. The small intestine including 2 tumors and 2 mesenteric lymph node metastases were resected. On histopathological examination, choriocarcinoma was diagnosed. The blood hCG level was remarkably elevated. The primary lesion could not be detected. Chemotherapy containing cisplatin(CDDP)and irinotecan(CPT-11)was initiated; although the blood hCG level was temporally lowered, the patient died of liver failure 8 months after the surgery.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antineoplastic Combined Chemotherapy Protocols* / therapeutic use
  • Choriocarcinoma* / drug therapy
  • Choriocarcinoma* / secondary
  • Cisplatin / administration & dosage
  • Humans
  • Intestinal Neoplasms* / drug therapy
  • Intestinal Neoplasms* / secondary
  • Irinotecan / administration & dosage
  • Liver Neoplasms* / drug therapy
  • Liver Neoplasms* / secondary
  • Male

Substances

  • Irinotecan
  • Cisplatin