Life Cycle of Childhood Asthma: Prenatal, Infancy and Preschool, Childhood, and Adolescence

Kristie R Ross; W Gerald Teague; Benjamin M Gaston

doi:10.1016/j.ccm.2018.10.008

Life Cycle of Childhood Asthma: Prenatal, Infancy and Preschool, Childhood, and Adolescence

Clin Chest Med. 2019 Mar;40(1):125-147. doi: 10.1016/j.ccm.2018.10.008. Epub 2018 Dec 20.

Authors

Kristie R Ross¹, W Gerald Teague², Benjamin M Gaston³

Affiliations

¹ Division of Pediatric Pulmonology, Allergy, Immunology and Sleep Medicine, Case Western Reserve University School of Medicine, 11100 Euclid Avenue, Cleveland, OH 44106, USA. Electronic address: Kristie.ross@uhhospitals.org.
² Pediatric Asthma Center of Excellence, Department of Pediatrics, University of Virginia School of Medicine, 409 Lane Road, Building MR4, Room 2112, PO Box 801349, Charlottesville, VA 22908, USA.
³ Division of Pediatric Pulmonology, Allergy, Immunology and Sleep Medicine, Rainbow Babies and Children's Hospital, Case Western Reserve University School of Medicine, Children's Lung Foundation, 2109 Adelbert Road, BRB 827, Cleveland, OH 44106, USA.

PMID: 30691707
DOI: 10.1016/j.ccm.2018.10.008

Abstract

Asthma is a heterogeneous developmental disorder influenced by complex interactions between genetic susceptibility and exposures. Wheezing in infancy and early childhood is highly prevalent, with a substantial minority of children progressing to established asthma by school age, most of whom are atopic. Adolescence is a time of remission of symptoms with persistent lung function deficits. The transition to asthma in adulthood is not well understood.

Keywords: Adolescence; Asthma; Childhood; Prenatal; Preschool; Puberty; Wheezing.

Publication types

Review

MeSH terms

Adolescent
Asthma / diagnosis*
Asthma / epidemiology*
Child
Child, Preschool
Female
Humans
Infant
Infant, Newborn
Male
Pregnancy
Prevalence
Respiratory Sounds / diagnosis*
Risk Factors