Abstract
Six new compounds, including three terpenoids (1-3) and three lignans (4-6), were isolated from the 95% EtOH extract of the twigs of Tripterygium hypoglaucum. Their structures were determined on the basis of extensive spectroscopic analysis. 9'-O-benzoyl-lariciresinol (4) showed weak cytotoxicity against HepG2/Adr cells, with an IC50 value of 30.1 μM in vitro.
Keywords:
Celastraceae; Tripterygium hypoglaucum; cytotoxicity; lignan; terpenoid.
MeSH terms
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Antineoplastic Agents / isolation & purification
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Antineoplastic Agents / pharmacology
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Furans / isolation & purification
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Furans / pharmacology
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Hep G2 Cells / drug effects
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Humans
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Inhibitory Concentration 50
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Lignans / chemistry
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Lignans / isolation & purification*
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Lignans / pharmacology
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Molecular Structure
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Plant Extracts / chemistry
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Plant Extracts / pharmacology
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Spectrum Analysis
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Terpenes / chemistry
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Terpenes / isolation & purification*
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Tripterygium / chemistry*
Substances
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Antineoplastic Agents
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Furans
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Lignans
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Plant Extracts
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Terpenes
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lariciresinol