Visible Light Photoredox Catalysis Using Ruthenium Complexes in Chemical Biology

Chemistry. 2019 May 10;25(27):6661-6672. doi: 10.1002/chem.201806024. Epub 2019 Feb 20.

Abstract

The development of bioorthogonal reactions have had a transformative impact in chemical biology and the quest to expand this toolbox continues. Herein we review recent applications of ruthenium-catalyzed photoredox reactions used in chemical biology.

Keywords: biochemistry; biorthogonal; catalysis; photoredox; ruthenium.

Publication types

  • Review

MeSH terms

  • Animals
  • Catalysis
  • Coordination Complexes / chemistry*
  • Coordination Complexes / metabolism
  • Light*
  • Morpholinos / chemistry
  • Oxidation-Reduction
  • Reactive Oxygen Species / chemistry
  • Receptors, Vascular Endothelial Growth Factor / antagonists & inhibitors
  • Receptors, Vascular Endothelial Growth Factor / metabolism
  • Ruthenium / chemistry*

Substances

  • Coordination Complexes
  • Morpholinos
  • Reactive Oxygen Species
  • Ruthenium
  • Receptors, Vascular Endothelial Growth Factor