[Diagnostic value of serum cystatin C and neutrophil gelatinase-associated lipocalin level in patients with acute renal injury secondary to cirrhosis]

G J Pang; Y J Wu; S Liu; H P Liu; S Y Liu

doi:10.3760/cma.j.issn.1007-3418.2019.01.015

[Diagnostic value of serum cystatin C and neutrophil gelatinase-associated lipocalin level in patients with acute renal injury secondary to cirrhosis]

Zhonghua Gan Zang Bing Za Zhi. 2019 Jan 20;27(1):65-67. doi: 10.3760/cma.j.issn.1007-3418.2019.01.015.

[Article in Chinese]

Authors

G J Pang¹, Y J Wu, S Liu, H P Liu, S Y Liu

Affiliation

¹ Clinical Laboratory, Third Central Hospital, Tianjin Key Laboratory of Artificial Cell, Artificial Cell Engineering Technology Research of public Health Ministry, Tianjin 300170, China.

PMID: 30685928
DOI: 10.3760/cma.j.issn.1007-3418.2019.01.015

Abstract

回顾性比较分析183例肝硬化患者中急性肾损伤（AKI）（136例）和非AKI患者（47例）血清胱抑素C（Cys-C）、中性粒细胞明胶酶相关脂质运载蛋白（NGAL）及尿NGAL表达水平，探讨AKI肝硬化患者血清中Cys-C、NGAL及尿NGAL对AKI的诊断价值，发现Cys-C和NGAL能反映肝硬化患者继发AKI时肾功能损害的严重程度，可作为肝硬化肾损伤早期诊断有效指标，且二者联合可提高肝硬化肾损伤的诊断效能。.

Keywords: Acute kidney injury; Cystatin C; Liver cirrhosis; Neutrophil gelatinase-related lipid transport protein.