Evaluation of early wound leakage as a risk factor for prosthetic joint infection

J Am Assoc Nurse Pract. 2019 Jun 5;31(6):337-343. doi: 10.1097/JXX.0000000000000159.

Abstract

Background and purpose: Prosthetic joint infection (PJI) is a serious complication resulting from total knee arthroplasty (TKA) or total hip arthroplasty (THA). In this study, patients with a PJI are compared with patients with an uncomplicated postoperative course to identify relevant risk factors for PJI.

Methods: A matched case-control study was performed with patients undergoing fast-track, elective unilateral TKA or THA. The following data were collected: demographics, surgery-related characteristics (perioperative blood loss, use of cement, body temperature), and postoperative characteristics (hematoma formation, wound leakage, blood transfusion, length of stay [LOS]).

Conclusions: When the PJI group was compared with the control group, there was significantly more wound leakage during hospital stay (88% vs. 36%, p = .001) and early wound dressing changes in the first 3 days after surgery (88% vs. 40%, p = .002). Hematoma formation was observed more in the PJI patients group (44% vs. 10%, p = .005). A trend test revealed a significant association between the total number of wound dressing changes and development of PJI (p < .001); 72% of PJI patients had a length of stay of ≥4 days compared with 34% of controls (odds ratio 10.5; 95% CI [2.1-52.3]; p = .004).

Implications for practice: Early postoperative wound drainage and hematoma formation directly correlate with PJI. This resulted in a significantly higher number of dressing changes and longer LOS. The nurse practitioner has a central role in postoperative care and is the first to recognize signs of an adverse postoperative clinical course.

MeSH terms

  • Aged
  • Arthroplasty, Replacement, Hip / methods
  • Arthroplasty, Replacement, Hip / statistics & numerical data
  • Arthroplasty, Replacement, Knee / methods
  • Arthroplasty, Replacement, Knee / statistics & numerical data
  • Artificial Limbs / microbiology
  • Artificial Limbs / standards*
  • Case-Control Studies
  • Drainage / adverse effects*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Odds Ratio
  • Risk Factors
  • Wound Infection / diagnosis*
  • Wound Infection / physiopathology
  • Wounds and Injuries / microbiology*
  • Wounds and Injuries / physiopathology