Coronary revascularization and use of hemodynamic support in acute coronary syndromes

Hellenic J Cardiol. 2019 May-Jun;60(3):165-170. doi: 10.1016/j.hjc.2019.01.010. Epub 2019 Jan 21.

Abstract

Cardiogenic shock develops in up to 10% of patients with acute myocardial infarction and continues to have high mortality. Early invasive treatment is the default therapeutic approach in these patients. On the basis of the results of the CULPRIT-SHOCK trial, culprit-only revascularization during the acute phase is preferred over multivessel revascularization. Routine use of intra-aortic balloon pump (IABP) is not recommended; however, the use of mechanical circulatory support has been increasing despite limited observational data to support its use. Several studies support multivessel revascularization in patients with uncomplicated ST-segment elevation acute myocardial infarction and simple nonculprit lesions to improve subsequent clinical outcomes.

Keywords: Acute coronary syndromes; Cardiogenic shock; Multivessel coronary artery disease; Non-STEMI; STEMI.

Publication types

  • Review

MeSH terms

  • Acute Coronary Syndrome / complications
  • Acute Coronary Syndrome / physiopathology
  • Acute Coronary Syndrome / therapy*
  • Hemodynamics / physiology*
  • Humans
  • Intra-Aortic Balloon Pumping*
  • Myocardial Revascularization / methods*
  • Shock, Cardiogenic / etiology
  • Shock, Cardiogenic / prevention & control*