Peach skin streaking is a previously undescribed skin discoloration affecting red-blush peach cultivars in Georgia and South Carolina. Streaked peach fruit have been observed in the field close to harvest. The cause of streaking is still unknown but one hypothesis is that atmospheric pollutants may be involved. The goal of this study was to establish proof of concept that commonly found air pollutants can produce streaks on peach skin similar to those observed in commercial orchards and investigate the susceptibility of peach fruit during maturation. Common reactive byproducts of atmospheric pollutants, including sulfuric acid (H2SO4), nitric acid (HNO3), and hypochlorite acid (HCl), at concentrations up to 10 μg/ml did not produce streaking under field conditions when applied at week 3, 2, and 1 prior to commercial harvest. However, sodium hypochlorite (NaClO) in the form of Clorox solution and chlorine dioxide (ClO2) at 100 μg/ml generated from the Aquamira water treatment solution produced streaking symptoms on detached peach fruit under controlled conditions and in the field. Peach fruit were most susceptible to streaking closest to harvest, suggesting that NaClO and ClO2 interfere with pigment formation.