West Nile virus (WNV) is an arthropod-transmitted flavivirus that causes West Nile fever and may infrequently cause neuroinvasive disease in humans. We present 2 cases of confirmed WNV infection, 1 of severe encephalitis and 1 of mild febrile illness, in a couple returning to the United Kingdom from South Africa.
Keywords: South Africa; United Kingdom; West Nile fever; West Nile neuroinvasive disease; West Nile virus; encephalitis; flavivirus; myositis; rhabdomyolysis; viruses.