Endocrine causes of recurrent pregnancy loss

Abstract

Objective: To review the available data on endocrine disorders and recurrent pregnancy loss.

Findings: Our group found that most endocrine disorders do not seem to be correlated with a diagnosis of recurrent pregnancy loss (RPL). The exception to this is testing for thyroid stimulating hormone and thyroid antibodies, which is recommended due to a strong correlation with recurrent pregnancy loss and positive anti-thyroid peroxidase antibodies.

Conclusion: The available literature supports testing thyroid function and antibodies in women with RPL. Testing for other endocrine disorders is only warranted if otherwise clinically indicated, independent from a history of recurrent pregnancy loss.

Keywords: Endocrine; Hypothyroidism; Recurrent pregnancy loss; Thyroid antibodies.