Brachytherapy: A critical component of primary radiation therapy for cervical cancer: From the Society of Gynecologic Oncology (SGO) and the American Brachytherapy Society (ABS)

Gynecol Oncol. 2019 Mar;152(3):540-547. doi: 10.1016/j.ygyno.2018.10.016. Epub 2019 Jan 18.

Abstract

Brachytherapy is well-established as an integral component in the standard of care for treatment of patients receiving primary radiotherapy for cervical cancer. A decline in brachytherapy has been associated with negative impacts on survival in the era of modern EBRT techniques. Conformal external beam therapies such intensity modulated radiation therapy (IMRT) or stereotactic body radiation therapy (SBRT) should not be used as alternatives to brachytherapy in patients undergoing primary curative-intent radiation therapy for cervical cancer. Computed tomography or magnetic resonance image-guided adaptive brachytherapy is evolving as the preferred brachytherapy method. With careful care coordination EBRT and brachytherapy can be successfully delivered at different treatment centers without compromising treatment time and outcome in areas where access to brachytherapy maybe limited.

Keywords: Brachytherapy; Cervical cancer; IMRT; Primary chemoradiation; SBRT.

Publication types

  • Review

MeSH terms

  • Brachytherapy / methods*
  • Brachytherapy / statistics & numerical data
  • Female
  • Humans
  • Radiosurgery / methods
  • Radiotherapy, Image-Guided / methods
  • Radiotherapy, Intensity-Modulated / methods
  • Uterine Cervical Neoplasms / diagnostic imaging
  • Uterine Cervical Neoplasms / mortality
  • Uterine Cervical Neoplasms / radiotherapy*