Prenatal determinants of childhood obesity: a review of risk factors 1

Can J Physiol Pharmacol. 2019 Mar;97(3):147-154. doi: 10.1139/cjpp-2018-0403. Epub 2019 Jan 19.

Abstract

Childhood obesity is a predictor of adult obesity and has its roots in the pre-pregnancy or pregnancy period. This review presents an overview of the prenatal risk factors for childhood obesity, which were categorized into 2 groups: biological risk factors (maternal pre-pregnancy body mass index, gestational weight gain, diabetes in pregnancy, and caesarean section), and environmental and behavioural risk factors (maternal smoking and exposure to obesogens, maternal dietary patterns, maternal intestinal microbiome and antibiotics exposure, and maternal psychosocial stress). Identifying modifiable predisposing prenatal factors for obesity will inform further development of inventions to prevent obesity over the life course, and future directions for research and intervention are discussed.

Keywords: body mass index; childhood; enfance; facteurs de risque; grossesse; indice de masse corporelle; obesity; obésité; pregnancy; risk factors.

Publication types

  • Review

MeSH terms

  • Animals
  • Female
  • Humans
  • Pediatric Obesity / etiology*
  • Pregnancy
  • Pregnancy Complications / etiology
  • Risk Factors