The Application of a New Model-Based Iterative Reconstruction in Low-Dose Upper Abdominal CT

Acad Radiol. 2019 Oct;26(10):e275-e283. doi: 10.1016/j.acra.2018.11.020. Epub 2019 Jan 17.

Abstract

Rationale and objectives: To compare upper abdominal computed tomography (CT) image quality of new model-based iterative reconstruction (MBIR) with low-contrast resolution preference (MBIRNR40), conventional MBIR (MBIRc), and adaptive statistical iterative reconstruction (ASIR) at low dose with ASIR at routine-dose.

Materials and methods: Study included phantom and 60 patients who had initial and follow-up CT scans. For patients, the delay phase was acquired at routine-dose (noise index = 10 HU) for the initial scan and low dose (noise index = 20 HU) for the follow-up. The low-dose CT was reconstructed with 40% and 60% ASIR, MBIRc, and MBIRNR40, while routine-dose CT was reconstructed with 40% ASIR. CT value and noise measurements of the subcutaneous fat, back muscle, liver, and spleen parenchyma were compared using one-way ANOVA. Two radiologists used semiquantitative 7-scale (-3 to +3) to rate image quality and artifacts.

Results: The phantom study revealed superior low-contrast resolution with MBIRNR40. For patient scans, the CT dose index for the low-dose CT was 3.00 ± 1.32 mGy, 75% lower than the 11.90 ± 4.75 mGy for the routine-dose CT. Image noise for the low-dose MBIRNR40 images was significantly lower than the low-dose MBIRc and ASIR images, and routine-dose ASIR images (p < 0.05). Subjective ratings showed higher image quality for low-dose MBIRNR40, with lower noise, better low-contrast resolution for abdominal structures, and finer lesion contours than those of low-dose MBIRc and ASIR images, and routine-dose ASIR images (p < 0.05).

Conclusion: MBIRNR40 with low-contrast resolution preference provides significantly lower noise and better image quality than MBIRc and ASIR in low-dose abdominal CT; significantly better objective and subjective image quality than the routine-dose ASIR with 75% dose reduction.

Keywords: Abdominal CT; Adaptive statistical iterative reconstruction; Model-based iterative reconstruction; Radiation dose; X-ray computed tomography.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Algorithms
  • Artifacts
  • Digestive System Diseases / diagnostic imaging*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Phantoms, Imaging
  • Radiation Dosage*
  • Radiographic Image Interpretation, Computer-Assisted / methods*
  • Radiography, Abdominal / methods*
  • Reproducibility of Results
  • Tomography, X-Ray Computed / methods*