Yield of CT pulmonary angiography in the diagnosis of acute pulmonary embolism: short report

BMC Res Notes. 2019 Jan 18;12(1):41. doi: 10.1186/s13104-019-4076-8.

Abstract

Objective: To assess computed tomography pulmonary angiography (CTPA) positive yield rate for pulmonary embolism (PE) in a Canadian academic tertiary center.

Results: This one-center retrospective cross-sectional study includes from 5565 (model 1) to 5296 (model 2) patients that were evaluated for suspected PE in 2015, among which 1331 (23.9% (model 1) to 25.1% (model 2)) underwent CTPA. Mean age of CTPA patients was 60.2 ± 16.6 years, of which 575 were males (43.2%). Two hundred eleven CTPA examinations were positive for PE, giving a CTPA positive yield rate of 15.9% (95% CI (13.93-17.87)). One hundred and thirteen (8.1%) CTPA were considered indeterminate, and eleven were considered nondiagnostic (0.8%). Among the 211 CTPA positive for PE, 67 (32%) were proximal emboli, 98 (47%) were segmental emboli and 44 (21%%) were subsegmental emboli. In conclusion, in this retrospective study done in a Canadian academic tertiary center, we report a positive rate of 15.9% for PE detection with CTPA, which is above the generally accepted lower threshold of 10% for the yield of CTPA.

Keywords: Computed tomography; Oversuse; Pulmonary embolism; Yield rate.

MeSH terms

  • Academic Medical Centers
  • Adult
  • Aged
  • Angiography / methods*
  • Angiography / statistics & numerical data
  • Canada
  • Cross-Sectional Studies
  • Female
  • Humans
  • Lung / blood supply
  • Lung / diagnostic imaging*
  • Male
  • Middle Aged
  • Pulmonary Embolism / diagnosis
  • Pulmonary Embolism / diagnostic imaging*
  • Retrospective Studies
  • Sensitivity and Specificity
  • Tertiary Care Centers
  • Tomography, X-Ray Computed / methods*
  • Tomography, X-Ray Computed / statistics & numerical data