Magnusiomyces clavatus infection in a child after allogeneic hematotopoetic stem cell transplantation: Diagnostic and therapeutic implications

Med Mycol Case Rep. 2018 Dec 21:23:65-67. doi: 10.1016/j.mmcr.2018.12.005. eCollection 2019 Mar.

Abstract

Magnusiomyces clavatus is an ascomycetous fungus causing invasive disease in immuno-compromised patients. Neutropenia, contaminated venous catheters, previous antifungal treatment are risk factors for this infection. We report a case of Magnusiomyces clavatus fungemia with pulmonary, renal and skin localizations in a 6-year-old boy with prolonged neutropenia because of three allogeneic hematopoietic stem cell transplantations. The infection was controlled by aggressive and strictly monitored combination therapy with voriconazole and liposomial-ampthotericine-B along with durable recover from neutropenia.

Keywords: Dimorphic fungi; HSCT; Magnusiomyces clavatus; Neutropenia.

Publication types

  • Case Reports