Synergic antibacterial coatings combining titanium nanocolumns and tellurium nanorods

Nanomedicine. 2019 Apr:17:36-46. doi: 10.1016/j.nano.2018.12.009. Epub 2019 Jan 14.

Abstract

Nanocolumnar titanium coatings have been fabricated in two sputtering systems with very different characteristics (a laboratory setup and semi-industrial equipment), thus possessing different morphologies (150 nm long columns tilted 20° from the normal and 300 nm long ones tilted 40°, respectively). These coatings exhibit similar antibacterial properties against Gram positive (Staphylococcus aureus) and Gram negative (Escherichia coli) bacteria. When a synergic route is followed and these coatings are functionalized with tellurium (Te) nanorods, the antibacterial properties are enhanced, especially for the long nanocolumns case. The biocompatibility is preserved in all the nanostructured coatings.

Keywords: Antibacterial properties; Biocompatibility; Magnetron sputtering; Nanostructured coatings.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / pharmacology*
  • Coated Materials, Biocompatible / chemistry
  • Coated Materials, Biocompatible / pharmacology*
  • Escherichia coli / drug effects
  • Escherichia coli Infections / prevention & control
  • Humans
  • Nanostructures / chemistry
  • Nanostructures / ultrastructure
  • Nanotubes / chemistry
  • Nanotubes / ultrastructure
  • Staphylococcal Infections / prevention & control
  • Staphylococcus aureus / drug effects
  • Tellurium / chemistry
  • Tellurium / pharmacology*
  • Titanium / chemistry
  • Titanium / pharmacology*

Substances

  • Anti-Bacterial Agents
  • Coated Materials, Biocompatible
  • Titanium
  • Tellurium