Efficacy of fluralaner spot-on solution for the treatment of Ctenocephalides felis and Otodectes cynotis mixed infestation in naturally infested cats

BMC Vet Res. 2019 Jan 16;15(1):28. doi: 10.1186/s12917-019-1775-2.

Abstract

Background: Cats can be infested with several ectoparasite species, especially Ctenocephalides felis and Otodectes cynotis. The aim of this study was to evaluate the efficacy of a single topical application of fluralaner against C. felis and O. cynotis natural infestation in stray (study 1) and owned (study 2) cats in central and southern Italy.

Results: The number of live fleas found on each cat on Day 0 ranged from 1 to more than 30 (arithmetic mean live flea count = 11.9 in study 1; 14.6 in study 2) while no live fleas were found on days 7 and 84 post topical application of fluralaner. The number of live mites found on each cat on Day 0 ranged from 1 to 42 (arithmetic mean live mite count = 6.4 in study 1; 8.9 in study 2) while no live mites were found on days 7 and 84 post topical application of fluralaner.

Conclusions: Topical fluralaner completely eliminated fleas and ear mites from infested cats and was 100% effective against both parasites up to 84 days after treatment.

Keywords: Cats; Ear mites; Ectoparasiticides; Fleas.

Publication types

  • Clinical Trial, Veterinary

MeSH terms

  • Acaricides* / administration & dosage
  • Administration, Topical
  • Animals
  • Cat Diseases / parasitology
  • Cats
  • Ctenocephalides*
  • Female
  • Flea Infestations / drug therapy
  • Flea Infestations / veterinary*
  • Isoxazoles* / administration & dosage
  • Male
  • Mite Infestations / drug therapy
  • Mite Infestations / veterinary*

Substances

  • A1443 compound
  • Acaricides
  • Isoxazoles