Demystifying Microglia: And Now the Work Begins

Leah C Dorman; Anna V Molofsky

doi:10.1016/j.immuni.2018.12.025

Demystifying Microglia: And Now the Work Begins

Immunity. 2019 Jan 15;50(1):11-13. doi: 10.1016/j.immuni.2018.12.025.

Authors

Leah C Dorman¹, Anna V Molofsky²

Affiliations

¹ Department of Psychiatry, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA; Neuroscience Graduate Program, University of California, San Francisco, San Francisco, CA, USA.
² Department of Psychiatry, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA; Neuroscience Graduate Program, University of California, San Francisco, San Francisco, CA, USA. Electronic address: anna.molofsky@ucsf.edu.

PMID: 30650371
DOI: 10.1016/j.immuni.2018.12.025

Abstract

Microglia actively shape the developing brain, but their transcriptional diversity is not well understood. Complementary studies by Hammond et al. (2018) and Li et al. (2019) characterize the microglial transcriptome at single cell resolution, highlighting their diversity during development, aging, and pathology.

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MeSH terms

Brain
Microglia*
Myeloid Cells
RNA*
Sequence Analysis, RNA

Substances

RNA