Algal production of nano-silver and gold: Their antimicrobial and cytotoxic activities: A review

J Genet Eng Biotechnol. 2016 Dec;14(2):299-310. doi: 10.1016/j.jgeb.2016.09.008. Epub 2016 Oct 6.

Abstract

The spreading of infectious diseases and the increase in incidence of drug resistance among pathogens have made the search for new antimicrobials inevitable, similarly is the cancer disease. Nowadays, there is a growing need for biosynthesized nanoparticles (NPs) as they are one of the most promising and novel therapeutic agents of biological origin. The unique physicochemical properties of the nano silver (Ag-NPs) as well as nano gold (Au-NPs) when combined with the growth inhibitory capacity against microbes lead to an upsurge in the research on NPs and their potential application as antimicrobials. The phytochemicals of marine algae that include hydroxyl, carboxyl, and amino functional groups can serve as effective metal reducing agents and as capping agents to provide a robust coating on the metal NPs. The biosynthesis of Ag-NPs and Au-NPs using green resources is a simple, environmentally friendly, pollutant-free and low-cost approach. The biosynthesized NPs using algae exerted an outstanding antimicrobial and cytotoxic effect.

Keywords: Algae; Antibacterial; Antifungal; Antiviral; Gold-nanoparticles; Silver-nanoparticles.

Publication types

  • Review