In recent years substantial efforts have been expended in extending thermodynamics to single quantum systems. Quantum effects have emerged as a resource that can improve the performance of heat machines. However in the fully quantum regime their implementation still remains a challenge. Here, we report an experimental realization of a quantum absorption refrigerator in a system of three trapped ions, with three of its normal modes of motion coupled by a trilinear Hamiltonian such that heat transfer between two modes refrigerates the third. We investigate the dynamics and steady-state properties of the refrigerator and compare its cooling capability when only thermal states are involved to the case when squeezing is employed as a quantum resource. We also study the performance of such a refrigerator in the single shot regime made possible by coherence and demonstrate cooling below both the steady-state energy and a benchmark set by classical thermodynamics.