Does State Dissociation Mediate the Relation Between Alcohol Intoxication and Deliberate Self-Harm?

Arch Suicide Res. 2020;24(sup1):231-242. doi: 10.1080/13811118.2018.1563577. Epub 2019 Mar 11.

Abstract

Research supports the notion that alcohol intoxication is a risk factor for deliberate self-harm (DSH). However, the underlying mechanisms for this relationship are poorly understood. We aimed to determine whether alcohol-induced dissociation mediated alcohol's effects on DSH. We used data from a dose-response study of alcohol intoxication and DSH to test the proposed model. Participants were assigned to reach target blood alcohol concentrations (BAC) ranging from 0.00% through 0.10% and then completed a behavioral measure of DSH. Dissociation was assessed using the Alcohol Dissociative Experiences Scale. BAC predicted both dissociation and DSH, but dissociation did not predict DSH. Although research on clinical populations suggests dissociation is related to DSH, our findings suggest dissociation does not mediate the effects of alcohol on self-harm.

Keywords: alcohol; dissociation; gender; intoxication; self-aggression; self-harm.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Alcoholic Intoxication / psychology*
  • Blood Alcohol Content
  • Dissociative Disorders / psychology*
  • Female
  • Humans
  • Male
  • Mediation Analysis
  • Middle Aged
  • Risk Factors
  • Self-Injurious Behavior / psychology*
  • Young Adult

Substances

  • Blood Alcohol Content