Urologic Oncology

Vet Clin North Am Small Anim Pract. 2019 Mar;49(2):311-323. doi: 10.1016/j.cvsm.2018.11.006. Epub 2019 Jan 8.

Abstract

Primary renal tumors are an uncommon diagnosis in small animals. Presentation, treatment, and prognosis depend on tumor type. Surgery with or without chemotherapy are the mainstays of treatment. Transitional cell carcinoma is the most common tumor of the urinary system. Clinical signs include hematuria, stranguria, and pollakiuria. Metastatic disease can develop over time within medial iliac lymph nodes, lungs, and vertebrae. Treatment of transitional cell carcinoma centers on chemotherapy with mitoxantrone, vinblastine, or carboplatin. Other agents used with success, include toceranib phosphate and chlorambucil. Interventional surgery, such as stenting and laser ablation, is used in a palliative setting addressing urinary obstruction.

Keywords: Bladder; Carcinoma; Neoplasia; Renal; Transitional cell carcinoma.

Publication types

  • Review

MeSH terms

  • Animals
  • Antineoplastic Combined Chemotherapy Protocols
  • Carcinoma, Transitional Cell / therapy
  • Carcinoma, Transitional Cell / veterinary
  • Cat Diseases / therapy*
  • Cats
  • Combined Modality Therapy / veterinary
  • Dog Diseases / therapy*
  • Dogs
  • Kidney Neoplasms / therapy
  • Kidney Neoplasms / veterinary
  • Urologic Neoplasms / therapy
  • Urologic Neoplasms / veterinary*
  • Veterinary Medicine