The impact of perampanel and targeting AMPA transmission on anti-seizure drug discovery

Expert Opin Drug Discov. 2019 Mar;14(3):195-197. doi: 10.1080/17460441.2019.1566318. Epub 2019 Jan 11.

Authors

Simona Lattanzi¹, Pasquale Striano²

Affiliations

¹ a Department of Experimental and Clinical Medicine, Neurological Clinic , Marche Polytechnic University , Ancona , Italy.
² b Pediatric Neurology and Muscular Diseases Unit, Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health , University of Genoa, "G. Gaslini" Institute , Genova , Italy.

PMID: 30633590
DOI: 10.1080/17460441.2019.1566318

No abstract available

Publication types

Editorial

MeSH terms

Animals
Anticonvulsants / adverse effects
Anticonvulsants / pharmacology*
Drug Discovery / methods
Epilepsy / drug therapy*
Epilepsy / physiopathology
Humans
Nitriles
Pyridones / adverse effects
Pyridones / pharmacology*
Receptors, AMPA / metabolism

Substances

Anticonvulsants
Nitriles
Pyridones
Receptors, AMPA
perampanel