Conversion Surgery for Unresectable Advanced Gastric Cancer: A Systematic Review and Meta-Analysis

Cancer Invest. 2019;37(1):16-28. doi: 10.1080/07357907.2018.1551898. Epub 2019 Jan 11.

Abstract

For patients with unresectable advanced gastric cancer, induction chemotherapy could down-stage primary tumors, resulting in conversion surgery becoming possible. However, the feasibility and therapeutic benefit of conversion surgery remains controversial. Therefore, this meta-analysis aimed to systematically review and investigate the efficacy of conversion surgery followed by chemotherapy for unresectable AGC.

Keywords: 1-year survival; 3-year survival; Conversion surgery; Meta-analysis; Unresectable advanced gastric cancer.

Publication types

  • Meta-Analysis
  • Systematic Review

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Humans
  • Induction Chemotherapy / methods*
  • Neoadjuvant Therapy
  • Prognosis
  • Stomach Neoplasms / drug therapy*
  • Stomach Neoplasms / pathology
  • Stomach Neoplasms / surgery*
  • Survival Analysis
  • Treatment Outcome