Non-ST elevation acute coronary syndrome in women and the elderly: recent updates and stones still left unturned

F1000Res. 2018 Nov 29:7:F1000 Faculty Rev-1865. doi: 10.12688/f1000research.16492.1. eCollection 2018.

Abstract

Despite the growing awareness of adverse events with acute coronary syndrome and vigilance to refine pharmacological and interventional therapies, the understanding of how these events present in and affect women and the elderly remains limited. Pathophysiological differences in these subgroups and under-representation in large trials create a medical gap in sex- and age-related outcomes and in our knowledge of how best to detect, diagnose, and treat acute coronary syndrome. This review provides a general overview of recent advances in non-ST elevation myocardial infarction management in women and the elderly and elucidates areas where further exploration is needed.

Keywords: acute coronary syndrome; elderly; non-ST elevation myocardial infarction; women.

Publication types

  • Review

MeSH terms

  • Acute Coronary Syndrome / diagnosis*
  • Acute Coronary Syndrome / therapy*
  • Adult
  • Aged
  • Aged, 80 and over
  • Disease Management
  • Female
  • Humans
  • Male
  • Myocardial Revascularization
  • Non-ST Elevated Myocardial Infarction / therapy*
  • Practice Guidelines as Topic
  • Risk Assessment
  • Risk Factors
  • Young Adult

Grants and funding

The author(s) declared that no grants were involved in supporting this work.