Synthesis of novel organic-inorganic hybrid fluorescent microspheres and their applications as Fe(III), Hg(II) and biothiols probes

Hao Zhang; Chen Nie; Jiahui Wang; Ruifang Guan; Duxia Cao

doi:10.1016/j.talanta.2018.11.082

Synthesis of novel organic-inorganic hybrid fluorescent microspheres and their applications as Fe(III), Hg(II) and biothiols probes

Talanta. 2019 Apr 1:195:713-719. doi: 10.1016/j.talanta.2018.11.082. Epub 2018 Nov 24.

Authors

Hao Zhang¹, Chen Nie¹, Jiahui Wang¹, Ruifang Guan², Duxia Cao³

Affiliations

¹ School of Materials Science and Engineering, University of Jinan, Jinan, Shandong 250022, China.
² School of Materials Science and Engineering, University of Jinan, Jinan, Shandong 250022, China. Electronic address: mse_guanrf@ujn.edu.cn.
³ School of Materials Science and Engineering, University of Jinan, Jinan, Shandong 250022, China. Electronic address: mse_caodx@ujn.edu.cn.

PMID: 30625606
DOI: 10.1016/j.talanta.2018.11.082

Abstract

Organic-inorganic hybrid fluorescent microspheres (OI-FMs) without typical fluorophores were prepared. Fluorescence quantum yield of OI-FMs is up to 70.0% after being heated in an oven at 120 °C (named as OI-FMs-120). Interestingly, OI-FMs-120 shows different detection performances in different solvents. It can be used for qualitative and quantitative detection of Fe^{3 +} with a detection limit of 37.8 nM in absolute ethanol. While in aqueous solution, it can be applied as an ON-OFF-ON fluorescent probe. Fluorescence of the probe is quenched by Hg^{2 +} and later recovered by biothiols. The detection limit is as low as 34.9 nM for Hg^{2 +}, 91.0 nM for Cys, 0.12 μM for Hcy and 0.13 μM for GSH in aqueous medium, respectively.

Keywords: Atypical fluorophores; Biothiols; Fluorescence microspheres; Heavy metal ions.