In vitro transcribed sgRNA causes cell death by inducing interferon release

Protein Cell. 2019 Jun;10(6):461-465. doi: 10.1007/s13238-018-0605-9.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • CRISPR-Cas Systems*
  • Cell Death
  • Gene Editing
  • HeLa Cells
  • Hematopoietic Stem Cells / cytology*
  • Humans
  • Interferons
  • RNA, Guide, CRISPR-Cas Systems
  • T-Lymphocytes / cytology*

Substances

  • Interferons