Protocells and LUCA: Transport of substances from first physicochemical principles

Abstract

Models of the transport of substances in protocells are considered from first physicochemical principles. Functional similarities and differences in the transport systems of archaea, cyanobacteria, E. coli, and diatoms have been analyzed. Based on the selection of the most important transport systems, a model of transport of substances through the membrane of the last universal common ancestor, LUCA, was constructed. Models of isotope separation in protocells were considered. Based on the proposed models, the difference in isotope concentrations in rocks can be predicted, which can serve as an indicator of the presence of life in the early stages of evolution. Mechanisms of energy conversion for the simplest forms of directed motion in protocells are considered. A special stage in the evolution of protocells is proposed - the minimal mobile cell.

Keywords: Archaea; Cell movement; Control of transport processes; LUCA; Minimal cell; Protocells.