Genome-wide analysis of the Aquaporin gene family in reptiles

Yu Zang; Jun Chen; Huaming Zhong; Jiayun Ren; Wangfeng Zhao; Qiang Man; Shuai Shang; Xuexi Tang

doi:10.1016/j.ijbiomac.2019.01.007

Genome-wide analysis of the Aquaporin gene family in reptiles

Int J Biol Macromol. 2019 Apr 1:126:1093-1098. doi: 10.1016/j.ijbiomac.2019.01.007. Epub 2019 Jan 3.

Authors

Yu Zang¹, Jun Chen¹, Huaming Zhong², Jiayun Ren³, Wangfeng Zhao⁴, Qiang Man⁴, Shuai Shang⁵, Xuexi Tang⁶

Affiliations

¹ College of Marine Life, Ocean University of China, Qingdao, Shandong, China.
² College of Life Science, Qufu Normal University, Qufu, Shandong, China.
³ Shandong Key Laboratory of Eco-Environmental Science for the Yellow River Delta, China; College of Biological and Environmental Engineering, Binzhou University, Binzhou, Shandong, China.
⁴ Shandong Key Laboratory of Eco-Environmental Science for the Yellow River Delta, China.
⁵ College of Marine Life, Ocean University of China, Qingdao, Shandong, China; Shandong Key Laboratory of Eco-Environmental Science for the Yellow River Delta, China; College of Biological and Environmental Engineering, Binzhou University, Binzhou, Shandong, China. Electronic address: shangshuai8983@126.com.
⁶ College of Marine Life, Ocean University of China, Qingdao, Shandong, China. Electronic address: tangxx@ouc.edu.cn.

PMID: 30611807
DOI: 10.1016/j.ijbiomac.2019.01.007

Abstract

Aquaporin (AQP) genes are widely distributed in plants, unicellular organisms, invertebrates and vertebrates. They play a critical role in the transport of water and other solutes across cell membranes. AQP genes have been identified and studied in many species but the AQPs of reptiles are unknown. Newly obtained genome assemblies provide an opportunity to identify the complete AQPs set and explore the evolutionary relationship of these genes. A total of 212 putative AQP genes were identified from 18 reptile species, including 20 partial genes and 192 intact genes. Phylogenetic results showed that 193 AQP genes could be classified into three major clades according to their subfamily. The divergence or phylogenetic distance between reptile AQP genes was closely related to traditional taxonomic groupings. Evolutionary analysis indicated the presence of positively selected sites in the AQP3 (P = 0.0104^⁎⁎) and AQP7 (P = 0.0202^⁎⁎) among land reptiles, suggesting their relationship to terrestrial environment adaptation.

Keywords: Aquaporin; Reptile; Terrestrial adaptation.

MeSH terms

Animals
Aquaporins / genetics*
Genome-Wide Association Study*
Multigene Family*
Phylogeny
Reptiles / genetics*
Selection, Genetic

Substances

Aquaporins